Anything that causes irritation, inflammation, fluid retention, or an abnormal growth in or around the carpal tunnel can cause carpal tunnel syndrome, including:
- Repetitive movements of the hands, wrists, or fingers—especially overactive use of a computer keyboard, certain musical instruments, or hand tools
- Use of vibrating equipment or tools
- A narrow carpal tunnel (due to heredity or other causes)
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Wrist injury:
- Burns
- Broken bones
- Compression or crush injuries
- Arthritis leading to swelling within the carpal tunnel
- Diabetes
- Raynaud's disease , which impairs blood flow in the hands
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Water retention due to:
- Kidney disease
- Amyloidosis
- Heart disease
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Hormone-related conditions, such as:
- Pregnancy
- Breastfeeding
- Menopause
- Hypothyroidism
- Cushing's disease
- Excess growth hormone
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Medications, such as:
- Birth control pills
- Cortisone pills or shots
- Some high blood pressure drugs
- Tumors and cysts in the carpal tunnel

